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Regional Prospective Observational Research in TB (RePORT) International and the Centers for AIDS Research (CFAR) Cross-Consortia Studies Elucidating the Role of HIV in TB Immunopathogenesis and Biomarker Discovery

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Regional Prospective Observational Research in TB (RePORT) International and the Centers for AIDS Research (CFAR) Cross-Consortia Studies Elucidating the Role of HIV in TB Immunopathogenesis and Biomarker Discovery

Thursday, February 21, 2019
Friday, November 9, 2018

CRDF Global is accepting proposals on behalf of the Division of AIDS at the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health to fund, collaborative global HIV/TB research projects across Regional Prospective Observational Research in TB (RePORT) International consortia (India, Brazil, Indonesia, South Africa, China and the Philippines) and the 19 Centers for AIDS Research (CFAR) allowing for work to extend across the 2 programs as well as sites and countries. The results of such research efforts will significantly impact HIV/TB clinical care and disease outcomes. Funding for this research award initiative is administered by CRDF Global, utilizing funds provided by U.S. National Institutes of Health (NIH).

RePORT International is a global network of observational cohorts and associated investigators with the goal of addressing local and global research priorities. RePORT International provides a platform for coordinated TB research by establishing a common set of standards and definitions; harmonized observational cohorts with well characterized populations; consolidated bio-specimen banks; and, integrated data collection and analysis strategies. To this end substantial progress has been made with each participating country supporting local research teams that have established RePORT cohorts with ongoing studies. This goal has been accomplished through establishment of integrated multi-disciplinary teams of collaborative investigators that have planned and continue to plan and conduct research across the spectrum of clinical research in TB.

Similarly, the CFAR program is a trans-NIH program that provides administrative and shared research support to synergistically enhance and coordinate high quality HIV research projects. CFARs accomplish this through centralized core facilities that provide cutting edge expertise, specialized resources and innovative technologies in a cost-effective and efficient manner.  The program emphasizes interdisciplinary and international collaboration across all areas of HIV research, including HIV/TB coinfection.